Theses undertaken at UMC

This page contains links to many of the theses undertaken at Uppsala Monitoring Centre.

21 documents found.

thesis

Utilizing Transformers with Domain-Specific Pretraining and Active Learning to Enable Mining of Product Labels

Master of Science Programme in Information Technology Engineering, Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Division of Scientific Computing. [Keywords : Machine Learning, Natural Language Processing, NLP, BERT, Active Learning, AL, Pharmacovigilance, UMC, Uppsala Monitoring Centre, Structured Product Label, SPL, Transformers, Domain-Specific Pretraining, NER, Named Entity Recognition, Adverse Drug Reaction, ADR]
Author: Erik Norén
Date: 2023-10-02
thesis

Named Entity Recognition for Case Narratives of Adverse Event Reports

Independent thesis Advanced level (degree of Master), Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology.
Author: Jayant Yadav
Date: 2023-06-01
thesis

Extracting drug indications from Structured Product Labels using Deep Learning techniques

Master's Thesis / Essay, Computational Cognitive Science, Rijksuniversiteit Groningen, Faculty of Science and Engineering.
Author: Magdalena Bilska
Date: 2022-10-01
thesis

Creation of a Next-Generation Standardized Drug Grouping for QT Prolonging Reactions using Machine Learning Techniques

Uppsala University, Master Programme in Engineering Physics. [Keywords : Pharmacovigilance, Adverse Drug Reactions, MedDRA, VigiBase, WHODrug Global, QT prolongation, Torsades de Pointes, Individual Case Safety Reports, Text Recognition, Standardised Drug Grouping, Multinomial Logistic Regression, BERT]
Author: Elsa Rådahl, Jacob Tiensuu
Date: 2021-06-01
thesis

Prediction of Drug Indication List by Machine Learning

Master of Arts degree in Statistics in the Faculty of Social Sciences, Uppsala University. [Keywords : regression tree, random forests, XGBoost, drug indication, support vector regression.]
Author: Bolin Wu
Date: 2021-06-01
thesis

Mapping medical expressions to MedDRA using Natural Language Processing

Independent thesis Advanced level (degree of Master), Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology. [Keywords : Classification, Machine Learning, ML, Natural Language Processing, NLP, BERT]
Author: Vanja Wallner
Date: 2020-11-01
thesis

Extracting Adverse Drug Reactions from Product Labels using Deep Learning and Natural Language Processing

Independent thesis Advanced level (degree of Master), KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health.
Author: Shachi Bista
Date: 2020-06-01
thesis

Improving the speed and quality of an Adverse Event cluster analysis with Stepwise Expectation Maximization and Community Detection

Independent thesis Advanced level, Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. [Keywords : Adverse Drug Reactions, Pharmacovigilance, Cluster Analysis, Stepwise Expectation Maximization, Community Detection, Topic Modelling]
Author: Nils Erlanson
Date: 2020-06-01
thesis

Retrospective disproportionality analysis to investigate the usefulness of the WHODrug Standardised Drug Groupings in the pharmacovigilance signal detection process

Independent thesis Advanced level (degree of Master), Uppsala University, Faculty of Pharmacy, Department of Pharmaceutical Biosciences (Pharmacometrics). [Keywords : pharmacovigilance, adverse event, adverse drug reaction, individual case safety report, signal]
Author: Iñigo Ortiz de Salazar
Date: 2020-01-01
thesis

Drug Name Recognition in Reports on Concomitant Medication

Independent thesis Advanced level, Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Division of Systems and Control. [Keywords : Machine Learning, Natural Language Processing, Drug Name Recognition, Classification]
Author: Arvid Gräns
Date: 2019-06-01
thesis

Deep Neural Networks for Inverse De-Identification of Medical Case Narratives in Reports of Suspected Adverse Drug Reactions

Independent thesis Advanced level (degree of Master), KTH, School of Electrical Engineering and Computer Science (EECS). [Keywords : De-Identification, Deep Learning, Recurrent Neural Networks, Natural Language Processing, Pharmacovigilance, Medical Language Processing, Privacy Protection, Adverse Drug Reactions]
Author: Eva-Lisa Meldau
Date: 2018-02-01
thesis

Investigating the scaleability of analyzing and processing RDBMS datasets with Apache Spark

Independent thesis Basic level (degree of Bachelor), Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science.
Author: Ferhat Bahceci
Date: 2018-02-01
thesis

Extraction of Severity Information from Clinical Narratives Using Statistical Natural Language Processing

Master’s thesis in Complex Adaptive Systems, Department of Signals and Systems, Chalmers University of Technology, Gothenburg, Sweden. [Keywords : natural language processing, information extraction, relation extraction, pharmacovigilance, machine learning]
Author: Rebecka Jacobsson
Date: 2016-09-01
thesis

Automatic de-identification of case narratives from spontaneous reports in VigiBase

Independent thesis Advanced level, Uppsala University, Department of Information Technology, Division of Computer Systems. [Keywords : de-identification, svm, crf, regex, VigiBase, i2b2]
Author: Jakob Sahlström
Date: 2015-09-01
thesis

Deviating time-to-onset in predictive models - detecting new adverse effects from medicines

Independent thesis Advanced level, Uppsala University, Disciplinary Domain of Science and Technology, Biology, Biology Education Centre. [Keywords : data mining, Kolmogorov-Smirnov test, predictive model, signal detection, time-to-onset]
Author: Caroline Wärn
Date: 2015-06-01
thesis

Quantitative methods to support drug benefit-risk assessment

Doctoral thesis. Department of Computer and Systems Sciences, Stockholm University
Author: Ola Caster
Date: 2014-03-21
thesis

Safety of Medication in Paediatrics

Doctoral thesis, Uppsala University, Department of Public Health and Caring Sciences
Author: Kristina Star
Date: 2013-05-16
thesis

Drug interaction surveillance using individual case safety reports

Doctoral thesis, Department of Medical and Health Sciences, Clinical Pharmacology. Linköping University, Faculty of Health Sciences. [Key words : Adverse drug reactions, adverse drug interaction surveillance, drug interactions, individual case safety reports, postmarketing pharmacovigilance, signal detection]
Author: Johanna Strandell
Date: 2011-09-07
thesis

Statistical methods for knowledge discovery in adverse drug reaction surveillance

PhD thesis, Stockholm University, Faculty of Science, Department of Mathematics
Author: Niklas Norén
Date: 2007-06-01
UMC material thesis

Seeing and Observing in International Pharmacovigilance - Achievements and Prospects in Worldwide Drug Safety

Doctoral thesis presented 2003, University of Nijmegen. Dr Marie Lindquist (pdf, 11 Mb).
Author: Marie Lindquist
Date: 2003-06-11
thesis

The use of a Bayesian Confidence Propagation Neural Network in pharmacovigilance

PhD thesis, Division of Clinical Pharmacology, Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Pharmacology. [Key words: adverse drug reactions, pharmacovigilance, signal detection, spontaneous reporting, data mining, Bayesian statistics, BCPNN, neural network]
Author: Andrew Bate
Date: 2003-06-07